Sr. Director, Compensation

The Sr. Director, Compensation is a critical leadership role on the HR team responsible for leading the design, development, and execution of our global compensation programs. This role will ensure our compensation offerings are market-competitive, performance-driven, and aligned with our business goals as a publicly traded biopharmaceutical company scaling for growth. The ideal candidate brings deep expertise in executive and broad-based compensation, strong analytical and governance capabilities, and experience working with a Compensation Committee of the Board. This individual will play a critical role in attracting, motivating, and retaining top talent while supporting the Company’s mission to bring innovative therapies to patients. This position requires a blend of strategic leadership, operational excellence, and deep expertise in compensation programs and practices, equity programs, and public company requirements.

Compensation Strategy & Governance

• Lead the strategy development and administration of broad-based and executive compensation programs, including base pay, incentives, and equity.
• Partner with the SVP of HR, executive management, and the Compensation Committee of the Board to design and recommend annual compensation strategies and policies.
• Oversee annual compensation cycles (merit, bonus, and equity planning), ensuring alignment with business performance and market competitiveness.
• Collaborate with Sales Operations team to ensure sales incentive compensation programs are effective and aligned to the Company’s overarching compensation philosophy.
• Lead the development of educational tools and resources, including the facilitation of training on compensation programs for the organization.
• Provide market analyses, benchmarking, and insights to guide talent and organizational decisions.
• Ensure compliance with SEC, IRS, and other regulatory requirements related to executive compensation and disclosures (e.g., CD&A, proxy statements).

Payroll Leadership

• Oversee global payroll operations, ensuring timely and accurate processing for all employees.
• Ensure compliance with federal, state, and international payroll tax laws and reporting requirements.
• Partner with Finance, HRIS, and Legal to ensure robust controls and audit readiness for all payroll and related processes.
• Drive process improvements, automation, and integration across HR, Finance, and systems platforms.

Systems, Data & Analytics

• Partner with HRIS to enhance system capabilities that support compensation and payroll processes in Workday or similar systems.
• Leverage data analytics to monitor pay equity, identify trends, and inform strategic decisions.
• Maintain high standards of data integrity, confidentiality, and auditability across all compensation and payroll systems.

Leadership & Collaboration

• Lead and develop a high-performing team across the compensation and payroll function.
• Establishes, directs, and allocates the necessary headcount and financial resources within the compensation and payroll function needed to support the company’s business strategy.
• Collaborate closely with HR colleagues, finance, legal, sales operations.
• Serve as a trusted advisor to senior management and the Board on compensation matters.
• Serves as back-up to Benefits & HRIS colleagues
• Participates in initiatives and/or other activities as required

• Bachelor’s degree in Business, Human Resources, Finance, or other related field required; Advanced degree, CCP or CECP certification highly desired
• Minimum 15 years of progressive experience in compensation, including executive compensation, equity programs, sales incentive compensation, market benchmarking and governance. Other relevant experience in HR such as HRIS, benefits and payroll a plus.
• 5+ years directly leading a team. Experience building and scaling teams preferred.
• Strong understanding of regulatory frameworks (FLSA, SEC, SOX, and tax compliance).
• Experience in a publicly traded company in the biotechnology, pharmaceutical industries
• Demonstrated ability to influence senior leaders and partner with Boards or Compensation Committees.
• Acumen for development of automated systems
• Proven success utilizing artificial intelligence to drive efficiencies and effectiveness in compensation management
• Advanced Excel and HRIS proficiency (such as pivot tables, vlookups and advanced formulas)
• Competencies: Leadership, Influencer, Professional Integrity, Discretion, Innovative, Independent Judgement, Teamwork/Collaboration, Verbal & Written Communication, Project Management, Attention to Detail, Analytical & Critical-Thinking Skills, Data Interpretation, Adaptability
• Working Conditions: Position may require periodic evening and weekend work, as necessary to fulfill obligations. Periodic overnight travel. This is a hybrid role based in Xeris’ Chicago office and requires a minimum of three days per week in the office. On-site requirement may change at management’s discretion.

The level of the position will be determined based on the selected candidate’s qualifications and experience.

#LI-HYBRID

As an equal employment opportunity and affirmative action employer, Xeris Pharmaceuticals, Inc. does not discriminate on the basis of race, color, religion, sex, gender identity, sexual orientation, national origin, age, disability, veteran status, genetics or any other characteristic protected by law.  It is our intention that all qualified applications are given equal opportunity and that selection decisions be based on job-related factors.

The anticipated base salary range for this position is $215,000 to $290,000. Final determination of base salary offered will depend on several factors relevant to the position, including but not limited to candidate skills, experience, education, market location, and business need. This role will include eligibility for bonus and equity. The total compensation package will also include additional elements such as multiple paid time off benefits, various health insurance options, retirement benefits and more. Details about these and other offerings will be provided at the time a conditional offer of employment is made. Candidates are always welcome to inquire about our compensation and benefits package during the interview process

NOTE:  This job description is not intended to be all-inclusive. Employee may perform other related duties as negotiated to meet the ongoing needs of the organization.